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CHANGES IN QUANTITATIVE EEG AND LOW RESOLUTION TOMOGRAPHY FOLLOWING CRANIAL ELECTROTHERAPY STIMULATION Richard C. Kennerly, B.A., M.A....

Dissertation Prepared for the Degree of DOCTOR OF PHILOSOPHY...

UNIVERSITY OF NORTH TEXAS August 2006...

APPROVED Eugenia Bodenhamer-Davis, Major Professor Jerry McGill, Committee Member Jan Holden, Committee Member Daniel C. Miller, Committee Member Joseph Doster, Chair of the Clinical Health Psychology Program In the Department of Psychology Linda Marshal, Chair of the Department of Psychology Sandra L. Terrell, Dean of the Robert B. Toulouse School of Graduate Studies...

Kennerly, Richard C., Changes in quantitative EEG and low resolution tomography following cranial electrotherapy stimulation. Doctor of Philosophy (Health Psychology and Behavioral Medicine), August 2006, 425 pp., 81 tables, 233 figures, 171 references. The effects of cranial electrotherapy stimulation (CES) on human EEG and brain current density were evaluated by quantitative electroencephalography (qEEG) and low resolution brain electromagnetic tomography (LORETA). A total of 72 research subjects were provided with a single session of CES, 38 were provided with 0.5 Hz CES while 34 were provided with 100 Hz CES. The qEEG paired t-tests revealed that in both frequencies of CES there was a significant (.05) increase in alpha relative power with concomitant decreases in delta and beta relative power. The 0.5 Hz CES decreased a wider frequency range of delta activity, while the 100 Hz CES decreased a wider frequency range of beta activity suggesting some difference may exist in the EEG response to different frequencies of CES. The changes found in qEEG relative power were consistent with the affective and cognitive effects of CES reported in the literature, such as increased relaxation and decreased anxiety. Statistically significant changes for qEEG values other than relative power, such as coherence, amplitude asymmetry, phase lag and power ratios were also found. The LORETA paired t-tests found statistically significant (.05) increases in cortical and subcortical theta and alpha frequency current density with concomitant decreases in delta and beta current density. The effects of CES on current density varied by frequency, but did not show a differential in response based on proximity to the contacts, or structures within the brain. Statistically significant changes in current density were found in all 2394 gray matter voxels represented by LORETA, indicat...

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